1b) This is part of a foundational 🫘 #MedEd #accredited series hosted by core @ckd_ce faculty @sophia_kidney & co-posted from @KIReports. See prior #tweetorials, still available for 🆓CE/#CME credit, at https://t.co/wBHAVb7FEi.
— @CKD_ce (@ckd_ce) February 21, 2024
3a) Hey #NephTwitter & #MedTwitter! Have you ever wondered about the mysteries of nighttime BP dips in #CKD? 🌙Let’s start with a quiz! What percentage of CKD patients are non-dippers?
— @CKD_ce (@ckd_ce) February 21, 2024
4) Healthy individuals typically dip BP 10-20% at night. This pattern is generated endogenously, follows a stable pattern, and is associated with higher sodium excretion during the day than at night.
— @CKD_ce (@ckd_ce) February 21, 2024
6) Past studies show that those with a non-dipping status tend to excrete relatively less sodium during the day. https://t.co/ngqrbY28kT
— @CKD_ce (@ckd_ce) February 21, 2024
8) This was a cross-sectional study that studied the relationship of blood pressure with day/night patterns of sodium and potassium excretion in 3152 patients with #CKD.
— @CKD_ce (@ckd_ce) February 21, 2024
🔎BP measured via #ABPM
🔎Na/K excretion measured by separate daytime and nighttime urine collections
10) Baseline characteristics of those in Q1 as compared to those in Q4:
— @CKD_ce (@ckd_ce) February 21, 2024
👉Older
🫘 Higher BMI
👉Higher fasting blood sugar
🫘 Higher % with #DM
👉Higher % with #CVD
🫘 More severe #albuminuria
👉More BP meds
🫘 Lower #eGFR
12) The authors considered multiple factors when interpreting #BP trends. Even when adjusting for demographics, #CVD, #eGFR, antihypertensives, immunosuppression, etc:
— @CKD_ce (@ckd_ce) February 21, 2024
📈Nighttime SBP 6.89mmHg Q1 > Q4
📈Nighttime DBP 4.25mmHg higher Q1 > Q4
📉Less dipping in Q1 than Q4 pic.twitter.com/OYdfnw0b8x
14) In conclusion, those in Q1
— @CKD_ce (@ckd_ce) February 21, 2024
– Exhibited ⬆️ 🧂 excretion during the 🌙 than Q4
– Higher 🌙 BP than Q4
– More non-dippers and risers than Q4
(illustration by @CTeodosiu) pic.twitter.com/qr4z9oZa6N
16) And now YOU 🫵 can dip into our 🏧 of CE/#CME credits and claim 0.5 hrs–all 🆓just for joining us and following this 🧵!
— @CKD_ce (@ckd_ce) February 21, 2024
Just go to https://t.co/iy9fi9gKXE and then FOLLOW US for more and more #MedEd!
17) This has been a tweetorial by @ghobby. Special thanks to @Sophia_Kidney, @brian_rifkin, and @NephroSeeker for help with this tweetorial, to @CTeodosiu for the fantastic illustrations, and to @ISNKidneyCare and @ckd_ce for the opportunity.
— @CKD_ce (@ckd_ce) February 21, 2024