2a) Statement of accreditation & faculty disclosures are listed at https://t.co/PHlIppl6Yw. Please also check out, for more 🆓credit, the #blogposts edited by @sophia_kidney at https://t.co/Zap2Al75YO.#MedTwitter #nephtwitter @ISNkidneycare
— @CKD_ce (@ckd_ce) October 24, 2023
3a) Let’s start with a quiz! Which of the following is a component of the Oxford classification system?
— @CKD_ce (@ckd_ce) October 24, 2023
a. #Tubulitis
b. #C1q staining
c. Endocapillary hypercellularity
d. Medullary angiitis
4) IgA nephropathy #IgAN is one of the most common primary glomerular diseases worldwide, with an incidence of 2.5 cases per 100k adults in the US population. 🔓 https://t.co/tduNWWCWyv
— @CKD_ce (@ckd_ce) October 24, 2023
6a) Time for another quiz! What is the strongest risk factor for progression in IgA #nephropathy?
— @CKD_ce (@ckd_ce) October 24, 2023
a. gross #hematuria
b. proteinuria
c. skin lesions
d. # of BP meds
7) Because of this, the revised Oxford classification (#MEST_C score) was created to utilize histological characteristics to predict outcomes.
— @CKD_ce (@ckd_ce) October 24, 2023
🔓https://t.co/l28NBbNzXg pic.twitter.com/xRJguSabI6
9) Few studies have reported a cross-section of histological & clinical characteristics at diagnosis. This recent @KIReports paper does precisely this!
— @CKD_ce (@ckd_ce) October 24, 2023
👉Retrospective cohort study
👉Evaluated biopsy and clinical data from adults w/ #IgAN
🔓 https://t.co/5C9Oztq2QJ pic.twitter.com/BXRyLQPaA0
11) Distribution of #MEST_C components displayed here. Note the highly variable characteristics: pic.twitter.com/FVjuidYDo4
— @CKD_ce (@ckd_ce) October 24, 2023
13) All MEST-C components were associated with #proteinuria. Proteinuria is the single strongest prognostic indicator for disease progression in #IgAN. pic.twitter.com/12JYZ7BpN6
— @CKD_ce (@ckd_ce) October 24, 2023
15) One limitation of the study is that #MEST_C scores are not validated for those with an #eGFR <30. This is especially important, given that a large number of those in the study had advanced CKD
— @CKD_ce (@ckd_ce) October 24, 2023
17) This has been a #tweetorial by @ghobby. Special thanks to @Sophia_Kidney @brian_rifkin and @NephroSeeker for help with this tweetorial and to @ISNKidneyCare for the opportunity to write this review.
— @CKD_ce (@ckd_ce) October 24, 2023
18) And you just earned 0.5hr 🆓 CE/#CME! You can claim your certificate at https://t.co/BZoxkNwg0a. Thanks for following this 🧵! Get more #MedEd #nephtwitter by FOLLOWING US here! And thanks to @kireports faculty @ghobby !
— @CKD_ce (@ckd_ce) October 24, 2023